| Title | Anticoagulation in pulmonary arterial hypertension - association with mortality, healthcare utilization, and quality of life: The Pulmonary Hypertension Association Registry (PHAR). |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Garry, JD, Kolaitis, NA, Kronmal, R, Thenappan, T, Hemnes, A, Grinnan, D, Bull, T, Chakinala, MM, Horn, E, Simon, MA, De Marco, T |
| Corporate/Institutional Authors | Pulmonary Hypertension Association Registry Investigators |
| Journal | J Heart Lung Transplant |
| Volume | 41 |
| Issue | 12 |
| Pagination | 1808-1818 |
| Date Published | 2022 Dec |
| ISSN | 1557-3117 |
| Keywords | Familial Primary Pulmonary Hypertension, Humans, Hypertension, Pulmonary, Patient Acceptance of Health Care, Pulmonary Arterial Hypertension, Quality of Life, Registries |
| Abstract | Routine long-term anticoagulation in PAH is controversial and shown to be beneficial or neutral in idiopathic disease (IPAH) and neutral-to-harmful in connective tissue disease (CTD-PAH). Authors sought examined the association between anticoagulation and mortality, healthcare utilization, and quality of life (QoL) in PAH using PHAR data. Anticoagulation was not associated with higher mortality, but is associated with increased healthcare utilization in the PHAR. PAH-specific QoL may be worse in patients receiving anticoagulation. |
| DOI | 10.1016/j.healun.2022.08.019 |
| Alternate Journal | J Heart Lung Transplant |
| PubMed ID | 36150996 |
| PubMed Central ID | PMC10329839 |
| Grant List | K24 HL155891 / HL / NHLBI NIH HHS / United States |
